| Typical Chemotherapy Doses | ||
|---|---|---|
| Name | Brand Name | Common Dose (m2 = meters squared) |
| Actinomycin D | Dactinomycin
Cosmegen |
0.5-1.0 mg/m2 IV infusion |
| Carboplatin | Paraplatin | 250-300 mg/m2 IV bolus (dogs)
10 mg/kg or 200-250 mg/m2 (cats) |
| Chlorambucil | Leukeran | Variable
2-6 mg/m2 PO daily |
| Cisplatin | Platinol | 30-70 mg/m2 IV drip with diuresis; Nephrotoxic NO CATS |
| Cyclophosphamide | Cytoxan | 200-250 mg/m2 IV or PO
50 mg/m2 PO 4 consecutive days/week; Metronomic 12-15 mg/m2 PO daily |
| Cytosine arabinoside | Cytosar | Variable
300-600 mg/m2 IV infusion |
| Doxorubicin | Adriamycin | 25-30 mg/m2 IV infusion 1 mg/kg IV infusion for small dogs and cats (<15kg) Cardiotoxic, do not exceed180 m/m2 cumulative dose |
| Lomustine | CCNU, CeeNU | Variable
40-80 mg/m2 (dog) 10 mg per dose (cat) Hepatotoxic |
| L-Asparaginase | Elspar | 400 u/kg IM or SQ, max dose 10,000 u |
| Melphalen | Alkeran | Variable
1.5-2 mg/m2 PO |
| Mitoxantrone | Novantrone | 5-6 mg/m2 IV infusion (dog); 5.5-6.5 mg/m2 IV infusion (cat) |
| Piroxicam | Feldene | 0.3 mg/kg PO daily |
| Prednisone | “Pred” | Variable
0.5-2 mg/kg PO daily |
| Procarbazine | Matulane | 50 mg/m2 PO |
| Rabacfosadine | Tanovea-CA1 | 0.85-1 mg/m2 IV infusion |
| Toceranib | Palladia | 2.5-2.75 mg/kg PO 3-4x/week |
| Vinblastine | Velban | 1.5-3 mg/m2 IV bolus |
| Vincristine | Oncovin | 0.50.75 mg/m2 IV bolus |
| Anaphlaxis/Allergic Reaction | |
|---|---|
| Diphenhydramine | 2.2 mg/kg (1 mg/#) |
| Dex SP | 0.1-0.2 mg/kg IV or IM |
| Extravasation | |
|---|---|
| Vincristine/Vinblastine: STOP |
|
| Doxorubicin: STOP |
|